Assafoetida, Asafetida, A Wei ้ฟ้ญ
Asafoetida, Devil’s Dung
Hing, Hingu (Ayurveda)
Perunkayam (Siddha)
A Wei ้ฟ้ญ (TCM)
Hilteet (Unani)
Shing kun เฝคเฝฒเฝเผเฝเฝดเฝ (Tibetan)


Ortus sanitatis, Cube, Johann von, 1501

Atlas der officinellen pflanzen (2), Felix, 1899

Lump of raw Asafetida gum
(Adam, 2022)
Members CLICK HERE for the PRO VERSION
Botanical name:
Ferula asafetida
Other related sources include F. sinkiangensis
Parts used:
Gum
‘The root has similar therapeutic functions’ (Li Shi Zhen)
Temperature & Taste:
Hot, dry. Pungent, bitter.
Classification:
2H. CARMINATIVES 2K. RESOLVENT 2Q. ANODYNE
3G. EMMENAGOGUE 3K. EXPECTORANT
4j. NERVINES
TCM:
J. Regulate Qi O. Promotes Digestion
Uses:
1. Warms the Womb, Moves Qi and Blood (West, Ayurveda):
-painful and difficult Menstruation
-chiefly for Suffocation of the Uterus: Hysteria and PMS
-“Dissolves the coagulated blood in the abdominal cavity” (Avicenna)
2. Warms the Stomach, Benefits Digestion (West, TCM, Ayurveda, Tibetan):
-indigestion, colic, abdominal pain, poor appetite
-taken before meals to strengthen a weak stomach
-Food Stagnation
-‘dissolves indigestion due to overeating of meat’. (Zhu Zhen Heng)
3. Clears Wind, Stops Spasms (West, Tibetan):
-good for Wind diseases from Wind-Phlegm / Wind-Damp
-Spasms, Convulsions, Epilepsy, Neurasthenia, Nervous Prostration, Depression, Insanity
-“Its actions in Epilepsy resemble those of Peony”. (Avicenna)
4. Warms the Kidneys (West, TCM, Ayurveda, Tibetan):
-Impotence, Premature Ejaculation, Spermatorrhea
-Arthritis, Edema (Tibetan Medicine)
5. Clears Cold Phlegm, Stops Cough (West, Ayurveda, Tibetan):
-spasmodic Cough, Asthma, chronic Bronchitis, Whooping Cough, Peri-pneumonia
-internal Abscesses (Avicenna)
-‘useful in internal tumours’ (Avicenna)
6. Clears Wind, Resists Poison (West, TCM, Ayurveda, Tibetan):
-used since ancient times as an antidote to Evil, Infectious and Epidemic diseases
-effective to prevent and treat Influenza; also Malaria
-“applied on bite of Rabid Dog as also on Insect stings particularly that of the Scorpion and Tarantula”. (Avicenna)
-‘disperses invading pathogenic Wind’ (Li Xun)
-antidote to Aconite and Opium poisoning; also other Poisons
-‘detoxifies toxin of all kinds of mushrooms and vegetables’. (Da Ming)
7. Kills Worms:
-used for Worms
–Gu syndrome (diseases caused by Parasites) (TCM)
8. Externally:
-Vulnerary; used for Wounds, Bruises
-externally for swelling of the Spleen, ‘suffocation of the Uterus’
-fumes of Asafetida and Goatโs horn, being burnt, was inhaled for Epilepsy
-smoke inhaled for Rhinitis and Sinusitis
-a small piece wrapped in linen or gauze can be put into the ear before sleep for Tinnitus.
-“Used as a kohl (collyrium) with honey, it proves beneficial in early stages of Cataract”. (Avicenna)
-“Corroded molars are filled with Asafetida or it is pasted with Frankincense on the teeth” (Avicenna)
-“Malignant necrotic swellings are scarified and asafetida is applied thereon with good results.” (Avicenna)
-“It is also a good remedy for the external and internal Abscesses”. (Avicenna)
Dose:
Correctives:
Substitute:
Preparation:
Main Combinations:
1. To promote Menstruation, cleanse the Uterus, to promote Labor, and for Hysteria;
i. Asafetida with … available in PRO version
ii. Asafetida with … available in PRO version
iii. Asafetida with … available in PRO version
iv. Asafetida with … available in PRO version
v. Asafetida with … available in PRO version
vi. Asafetida, … available in PRO version
2. Hysteria:
i. Asafetida with … available in PRO version
ii. Asafetida … available in PRO version
iii. Asafetida with … available in PRO version
iv. Asafetida with … available in PRO version
v. and to strongly promote Menstruation, combine Asafetida with … available in PRO version
vi. Asafetida with … available in PRO version
vii. Asafetida with … available in PRO version
viii. Asafetida, … available in PRO version
3. Infertility, Asafetida with … available in PRO version
4. Asthma or Bronchitis:
i. combine Asafetida with … available in PRO version
ii. Asafetida with … available in PRO version
iii. spasmodic Cough, Whopping Cough, Asafetida, … available in PRO version
5. Wind diseases: combine Asafetida with … available in PRO version
6. Epilepsy, Seizures:
i. Asafetida with … available in PRO version
ii. Asafetida with … available in PRO version
7. Nervous diseases, Spasms:
i. Neurosis, Asafetida with … available in PRO version
ii. Asafetida with … available in PRO version
iii. Asafetida with … available in PRO version
8. Hypochondriac Melancholy, Asafetida with … available in PRO version
9. Abdominal Obstruction, Asafetida, … available in PRO version
10. To promote Digestion and increase digestive Heat, Asafetida with … available in PRO version
11. All Wind diseases of the digestive system: combine Asafetida with … available in PRO version
12. Heart disorders from Wind, Heart pain, Asafetida, … available in PRO version
13. Diarrhea associated with weakness of the Stomach, combine Asafetida with … available in PRO version
14. Dysentery, Asafetida, … available in PRO version
15. Chronic Malaria, Asafetida with … available in PRO version
16. Abscesses, Carbuncles etc., combine Asafetida with … available in PRO version
17. In enemas, Asafetida with … available in PRO version
Major Formulas
Asafetida 25 (Shin kun nyer lnga) (Tibetan Medicine)
Mental Happiness (Sems kyi bde skyid) (Tibetan Medicine)
Cautions:
1. Best not used during pregnancy (despite having been used for Threatened Miscarriage)
2. Not used in Heat conditions.
Toxicity:
1. Evaluation of Toxicity Effects of Asafetida on Biochemical, Hematological, and Histological Parameters in Male Wistar Rats
2. Acute and subchronic toxicity assessment model of Ferula assa-foetida gum in rodents
3. . Sub-acute and acute toxicity of Ferula asafoetida and Silybum marianum formulation and effect of the formulation on delaying gastric emptying
4. Severe Methemoglobinemia Secondary to Ferula asafoetida Ingestion in an Infant: A Case Report
Main Preparations used:
Pills of Asafetida (either alone, made up with Distilled Vinegar, or Compound)
Pharmacographia, Fluckiger & Hanbury, 1879
‘Whether the substance which the ancients called Laser was the same as the modern Aasafoetida, is a question that has been often discussed during the last three hundred years, and it is one upon which we shall attempt to offer no further evidence. Suffice it to say that Laser is mentioned along with products of India and Persia, among the articles on which duty was levied at the Roman custom house of Alexandria in the 2nd century.
“Hingu,” doubtless meaning Asafoetida, occurs in many Sanskrit works, especially in epic poetry, but also in Susruta.
Asafoetida was certainly known to the Arabian and Persian geographers and travellers of the middle ages. One of these, Ali Istakhri, a native of Istakir, the ancient Persepolis, who lived in the 10th century, states that it produced abundantly in the desert between Sistan and Makran, and is much used by the people as a condi-ment. The region in question comprises a portion of Beluchistan.
The geographer Edrisi, who wrote about the middle of the 12th century, asserts that asafoetida, called in Arabic Hiltit, is collectedย largely in a district of Afghanistan near Kaleh Bust, at the junction of the Helmand with the Arghundab, a locality still producing the drug. Other Arabian writers as quoted by Ibn Baytar, describe asafoetida in terms which show it to have been well known and much valued.
Matthaeus Platearius, who flourished in the second half of the 12th century, mentions asafoetida in his work on simple medicines, known as Circa installs, which was held in great esteem during the middle ages. It is also named a little later by Otho of Cremona, who remarks that the more foetid the drug, the better its quality. Like other productions of the East, asafoetida found its way in European commerce during the middle ages through the trading cities of Italy. It is worthy of remark that it is much less frequently mentioned by the older writers than galbanum, sagapenum and opopanax. In the 13th century, the “Physicians of Myddfai,” in Wales, considered asafoetida as one of the substances which every physician “ought to know and use.”
GENERAL / REVIEW
โBiological activities and medicinal properties of Asafoetida: A review
โFerula asafoetida: Traditional uses and pharmacological activity
โMetabolic Profile, Bioactivities, and Variations in the Chemical Constituents of Essential Oils of the Ferula Genus (Apiaceae)
ANTIMICROBIAL / ANTIBACTERIAL
โBiological activities and medicinal properties of Asafoetida: A review
โIn Vitro Antioxidant and Bactericidal Efficacy of 15 Common Spices: Novel Therapeutics for Urinary Tract Infections?
โAntibacterial activity of some Indian Ayurvedic preparations against enteric bacterial pathogens
โAntimicrobial Activity of the Essential Oil Obtained from the Seed and Oleo-Gum-Resin of Ferula Assa-Foetida against Oral Pathogens
ANTI-VIRAL
โAnti-Viral Evaluation of Sesquiterpene Coumarins from Ferula assa-foetida against HSV-1
โAntiviral Potential of Selected Medicinal Herbs and Their Isolated Natural Products
โThe human rhinovirus: humanโpathological impact, mechanisms of antirhinoviral agents, and strategies for their discovery
โPotential Immunomodulatory Properties of Biologically Active Components of Spices Against SARS-CoV-2 and Pan ฮฒ-Coronaviruses
โAnti-Viral Evaluation of Sesquiterpene Coumarins from Ferula assa-foetida against HSV-1
ANTIOXIDANT
โIn Vitro Antioxidant and Bactericidal Efficacy of 15 Common Spices: Novel Therapeutics for Urinary Tract Infections?
โAntiepileptic and Antioxidant Effect of Hydroalcoholic Extract of Ferula Assa Foetida Gum on Pentylentetrazole- induced Kindling in Male Mice
โThe effect of hydroalcoholic extract of Ferula foetida stems on blood pressure and oxidative stress in dexamethasone-induced hypertensive rats
ANTINOCICEPTIVE
โFerula asafoetida: Traditional uses and pharmacological activity
โAntinociceptive effect of Ferula assa-foetida oleo-gum-resin in mice
ANTHELMINTIC
โBiological activities and medicinal properties of Asafoetida: A review
โEvaluation of anti-helmintic activity of Ferula foetida โHing- A natural Indian spiceโ aqueous extract
LEISHMANIASIS
โAntileishmanial activity of Ferula assa-foetida oleo gum resin against Leishmania major: An in vitro study
โIn vitro Antileishmanial Activity of Some Ethiopian Medicinal Plants
PROMOTES DIGESTION
โBiological activities and medicinal properties of Asafoetida: A review
DYSPEPSIA
โSafety and Efficacy of Ferula asafoetida in Functional Dyspepsia: A Randomized, Double-Blinded, Placebo-Controlled Study
HEPATOPROTECTIVE
โBiological activities and medicinal properties of Asafoetida: A review
HYPOTENSIVE / ANTI-HYPOTENSIVE
โBiological activities and medicinal properties of Asafoetida: A review
โAntihypertensive Effects of Standardized Asafoetida: Effect on Hypertension Induced by Angiotensin II
โThe effect of hydroalcoholic extract of Ferula foetida stems on blood pressure and oxidative stress in dexamethasone-induced hypertensive rats
NEUROPROTECTIVE
โBiological activities and medicinal properties of Asafoetida: A review
โFerulic acid attenuates microglia-mediated neuroinflammation in retinal degeneration
โPreventive Effect of Ferula asafoetida Oleo Gum Resin on Histopathology in Cuprizone-Induced Demyelination Mice
โNeuroprotective potency of some spice herbs, a literature review
MEMORY PROMOTING
โBiological activities and medicinal properties of Asafoetida: A review
ANXIOLYTIC
โBiological activities and medicinal properties of Asafoetida: A review
RELAXANT
โBiological activities and medicinal properties of Asafoetida: A review
ANTISPASMODIC / ANTICONVULSANT
โThe Relaxant Effect of Seed’s Essential Oil and Oleo-Gum-Resin of Ferula Assa-Foetida on Isolated Rat’s Ileum
โAnticonvulsant Effect of Ferula Assa-Foetida Oleo Gum Resin on Chemical and Amygdala-Kindled Rats
EPILEPSY
โAntiepileptic and Antioxidant Effect of Hydroalcoholic Extract of Ferula Assa Foetida Gum on Pentylentetrazole- induced Kindling in Male Mice
โEfficacy of Iranian Traditional Medicine in the Treatment of Epilepsy
MULTIPLE SCLEROSIS
โPreventive Effect of Ferula asafoetida Oleo Gum Resin on Histopathology in Cuprizone-Induced Demyelination Mice
OPIOID ADDICTION
โTraditional Chinese and Indian medicine in the treatment of opioid-dependence: a review
โEffect of the methanolic extracts of different parts of Ferula assa-foetida on naloxone-induced withdrawal behavior in morphine-dependent mice
MYOCARDIAL ISCHEMIA
โThe effect of asafoetida essential oil on myocardial ischemic-reperfusion injury in isolated rat hearts
VASORELAXANT
โRole of the potassium channels in vasorelaxant effect of asafoetida essential oil
DIURETIC
โEffect of Ferula assa-foetida oleo-gum-resin on renal function in normal Wistar rats
INCREASES SPERM
โBiological activities and medicinal properties of Asafoetida: A review
โEffect of Ferula assa-foetida oleo gum resin on spermatic parameters and testicular histopathology in male wistar rats
IMPOTENCE / ERECTILE DYSFUNCTION
โA panoramic view of medicinal plants traditionally applied for impotence and erectile dysfunction in Persian medicine
DIABETES
–Biological activities and medicinal properties of Asafoetida: A review
โMiddle East Medicinal Plants in the Treatment of Diabetes: A Review
OBESITY
โBiological activities and medicinal properties of Asafoetida: A review
INCREASES PROGESTERONE
โFerula asafoetida: Traditional uses and pharmacological activity
ANTI-IMPLANTATION
โFerula asafoetida: Traditional uses and pharmacological activity
CANCER
โBiological activities and medicinal properties of Asafoetida: A review
โFerula asafoetida: Traditional uses and pharmacological activity
โGummosin, a sesquiterpene coumarin from Ferula assa-foetida is preferentially cytotoxic to human breast and prostate cancer cell lines
โCytotoxic Properties of Some Medicinal Plant Extracts from Mazandaran, Iran
โCytotoxic activity of the genus Ferula (Apiaceae) and its bioactive constituents
โAntitumor effect of Ferula assa foetida oleo gum resin against breast cancer induced by 4T1 cells in BALB/c mice
โEvaluation of Cytotoxicity Effects of Oleo-Gum-Resin and Its Essential Oil of Ferula assa-foetida and Ferulic Acid on 4T1 Breast Cancer Cells



